Speaker: Martin Jarrold, Indiana University
Topic: Charge Detection Mass Spectrometry: Recent Developments and Applications
Date: Monday, May 17th, 2021
Time: 1:00 PM EDT Presentation
Location: Webinar – see emails on May 6 and 13 for invite link. Join the mailing list
Abstract: Charge detection mass spectrometry (CDMS) provides a way to measure accurate masses for heterogeneous samples into the gigadalton regime. It is a single particle technique where the mass of each ion is determined from simultaneous measurements of its mass to charge ratio (m/z) and charge. CDMS opens the door to the analysis of high mass, heterogeneous samples such as vaccines and gene therapy products. Recent developments in instrumentation that have improved the resolution and speed of CDMS measurements will be described along with several recent examples of applications to the analysis of bio-pharmaceuticals, and virus assembly and disassembly.