{"id":509,"date":"2009-01-22T09:45:09","date_gmt":"2009-01-22T14:45:09","guid":{"rendered":"http:\/\/wbmsdg.org\/wordpress\/?p=509"},"modified":"2009-01-22T11:31:32","modified_gmt":"2009-01-22T16:31:32","slug":"january-26-2009-wbmsdg-meeting","status":"publish","type":"post","link":"https:\/\/wbmsdg.org\/?p=509","title":{"rendered":"January 26, 2009 WBMSDG Meeting"},"content":{"rendered":"<p class=\"MsoNormal\"><strong>Speaker<\/strong>: <strong>Dr. Xudong Yao, <\/strong>Department of Chemistry, University of Connecticut, Storrs, CT<\/p>\n<p><strong>Topic<\/strong>: <span style=\"font-size: small; font-family: Times New Roman;\"><span style=\"font-size: 12pt;\">Fragment Ion Mass Defect Labeling (FIMDL) of Peptides for Proteome Analysis<\/span><\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"font-size: small; font-family: Times New Roman;\"><span style=\"font-size: 12pt;\"><strong>Abstract<\/strong>: Fragment ion mass defect labeling (FIMDL) together with averagine-scaling analysis promises important impact on mass spectrometry-based proteomics. This strategy effectively uses the broad and unoccupied mass spaces in the low m\/z region of mass spectra for interference-free peptide analysis and fast data complexity reduction. Located in these unoccupied zones, small peptide fragments with FIMDL groups are generated by combining solution modification with gas-phase reaction. Various iodine- and other halogen-containing reagents are surveyed as FIMDL reagents. Modified peptides show three different classes of gas-phase fragmentation characteristics, as revealed by tandem and energy-resolved mass spectrometry. Distinct potential applications of different modifications in advanced proteome analysis will also be discussed.<\/span><\/span><\/p>\n<p><strong> Time<\/strong>: 7:30 pm<strong><\/strong><\/p>\n<p><strong>Dinner: <\/strong><span style=\"font-size: small; font-family: Times New Roman;\"><span style=\"font-size: 12pt;\">Please join Miquel Antoine and the speaker for dinner at the Ram&#8217;s Head Tavern at Savage Mill, 8600 Foundry Street, Savage, MD 20763 at 5:30 pm.\u00a0 Contact Miquel at Miquel.Antoine@jhuapl.edu and let her know you will be there.<\/span><\/span><\/p>\n<p><strong>Location<\/strong>: Shimadzu Scientific Instruments, Inc. Training Center, 7100 Riverwood Drive, Columbia, MD 21046.<br \/>\n<strong><br \/>\nDirections<\/strong>: <a href=\"https:\/\/wbmsdg.org\/wordpress\/?p=209\">Shimadzu Scientific Instruments<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Speaker: Dr. Xudong Yao, Department of Chemistry, University of Connecticut, Storrs, CT Topic: Fragment Ion Mass Defect Labeling (FIMDL) of Peptides for Proteome Analysis Abstract: Fragment ion mass defect labeling (FIMDL) together with averagine-scaling analysis promises important impact on mass &hellip; <a href=\"https:\/\/wbmsdg.org\/?p=509\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[83,90],"class_list":["post-509","post","type-post","status-publish","format-standard","hentry","category-meetings","tag-2009-meeting-schedule","tag-meetings"],"_links":{"self":[{"href":"https:\/\/wbmsdg.org\/index.php?rest_route=\/wp\/v2\/posts\/509","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wbmsdg.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wbmsdg.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wbmsdg.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wbmsdg.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=509"}],"version-history":[{"count":0,"href":"https:\/\/wbmsdg.org\/index.php?rest_route=\/wp\/v2\/posts\/509\/revisions"}],"wp:attachment":[{"href":"https:\/\/wbmsdg.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=509"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wbmsdg.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=509"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wbmsdg.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=509"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}