FeMS+ “Out of the Shadows” Leadership Development Program

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Females in Mass Spectrometry (FeMS+) is hosting a one-day leadership event in Rockville, MD for women scientists.

FeMS+ is a community-led initiative to create a worldwide network of support for women in mass spectrometry. “Out of the Shadows” is our premiere Leadership Development program for women in mid- to senior-level positions aiming to advance their career. Since 2023, we have held four “Out of the Shadows” events, in San Jose, US; Munich and Hamburg, Germany; and Singapore.

The “Out of the Shadows” event will be held on Tuesday September 10, 2024 in Rockville, MD, co-sponsored by CASSS and SCIEX. Registration is free. Application is now open and will close on July 30, 2024. To apply, please visit https://femalesinms.com/out-of-the-shadows-leadership-development-program/ The September leadership event focuses on powering up executive presence. There will be interactive professional coaching, practical exercises, and group discussion.

FeMS-OTS-Cohort-6-Flyer-1

Chemical Tags for Quantitative Omics Workshop

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August 2, 2024
University of Wisconsin – Madison on Zoom

This interactive workshop will cover the fundamentals of chemical tagging for quantifying -omics on a mass spectrometer.
This is a beginner level workshop, open to anyone who has at least six months of mass spec experience. This workshop will be a mix of lectures, demos, and discussion, topics include:
· Fundamentals and overview of chemical labeling approaches to quantitative proteomics
· Data Analysis Lecture
· Research Lecture on High-throughput quantitative top-down proteomics using intact protein-level tandem mass tag (TMT) labeling
· Applications of DiLeu tags for quantitative PTM analysis and biomarker discovery
· Development and application of isobaric tags for quantitative glycomics and lipidomics
· Research Lecture on Unlocking the secrets of complex proteotypes with sample multiplexing-based quantitative proteomics

Registration can be found at https://www.ncqbcs.com/resources/training/tagging-training/

There is no cost to attend due to generous support from the National Institutes of Health and the National Center for Quantitative Biology of Complex Systems (P41 GM108538).
Omics_Workshop_Schedule

June 2024 Meeting

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Topic: Post-ASMS Poster Night and ASMS Travel Award Presentations
All attendees are invited to put up an ASMS poster

Date: Monday, June 17, 2024

Time: 6:15 pm Dinner and ASMS posters, 7:30 pm Presentations

Location: Shimadzu Scientific Instrument, Inc. Training Center 7100 Riverwood Drive, Columbia, MD 21046 (Directions)

Dinner: Please RSVP to Jonathan Ferguson (jonathan.ferguson33@gmail.com) by Friday, June 14 if you will be attending the dinner.

ASMS Travel Award Recipients:

    • Melissa Leyden, University of Virginia

: “Characterization of Insect Sperm Nuclear Basic Proteins by Liquid Chromatography – Tandem Mass Spectrometry”

    • Juliet Obi, University of Maryland Baltimore

: “A Structural and Dynamic Basis for the Interactions of the Dengue Nonstructural (NS5) Protein with Stem Loop A (SLA)”

    • Bay Xu, Johns Hopkins University

: “SPOT: Spatial Proteomics through On-site Tissue-protein-labeling”

2024 Washington-Baltimore MSDG Young Investigator Travel Award Recipients

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Congratulations to the following recipients of the WBMSDG Young Investigator Travel Awards traveling to ASMS:

Melissa Leyden, University of Virginia (Advisor: Don F. Hunt), 1st place: “Characterization of Insect Sperm Nuclear Basic Proteins by Liquid Chromatography – Tandem Mass Spectrometry”

Juliet Obi, University of Maryland Baltimore (Advisor: Daniel Deredge), 2nd place: “A Structural and Dynamic Basis for the Interactions of the Dengue Nonstructural (NS5) Protein with Stem Loop A (SLA)”

Bay Xu, Johns Hopkins University (Advisor: Hui Zhang), 3rd place: “SPOT: Spatial Proteomics through On-site Tissue-protein-labeling”

May Meeting

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Speaker: Hui Zhang, Johns Hopkins University

Topic: Glycoproteomics: methods and applications in clinical proteomics

Date: May 20, 2024

Time: 6:15 pm Dinner, 7:15 pm Presentation

Location: Shimadzu Scientific Instrument, Inc. Training Center 7100 Riverwood Drive, Columbia, MD 21046 (Directions)

Dinner: Please RSVP to Jonathan Ferguson (jonathan.ferguson33@gmail.com) by Friday, May 17 if you will be attending the dinner.

Abstract: The integration of proteomic technologies into clinical practice indeed holds significant promise for revolutionizing disease diagnosis, prognosis, and treatment. By delving into the intricate world of proteins and their modifications, particularly protein glycosylation, researchers aim to unravel the complexities underlying various diseases.
Glycoproteomics, a specialized field within proteomics and glycomics, focuses on the comprehensive characterization of glycoproteins. In recent years, mass spectrometry-based technologies have emerged as the cornerstone of advancements in glycoproteomics. One of the main challenges in glycoproteomics lies in the heterogeneity of glycosylation of glycoproteins, including variations in glycan types, sites of glycosylation, and the specific glycans attached to each glycosylation site. To overcome these challenges, we have developed various methodologies in glycoprotein glycopeptide enrichment, liquid chromatography, mass spectrometry, and software tools, for precise site-specific glycan assignments.
The developed glycoproteomic techniques offer unprecedented opportunities to investigate the interplay between genomic, environmental factors, and protein modifications. By employing these advanced technologies to investigate tumors, we have gained invaluable insights into cancer biology, particularly pertaining to protein modifications such as glycosylation.
In summary, the integration of glycoproteomic approaches into biomedical research has the potential to significantly advance our understanding of cancer and pave the way for more personalized and effective clinical interventions.
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lightning talk
Ying Hao, Ph.D. (NIH/NIA/IRP)