Thursday, April 25th, 2019

Available Positions


University of Maryland: Assistant Research Scientist

MedImmune: Research Bioinformatics Scientist

MedImmune: Postdoctoral Fellow – Proteomics/Metabolomics

MedImmune: Postdoctoral Fellow – Proteomics

MedImmune: Scientist I – Metabolomics

MedImmune: Senior Scientist – Proteomics/Metabolomics

Waters: Mass Spectrometry Sales Specialist

MilliporeSigma: Scientist, Product Characterization

USDA: Postdoctoral Associate

FDA CBER: Postdoctoral Fellow

Georgetown University Medical Center: Analytical Scientist

Georgetown University: Postdoctoral Fellow/Research Associate/Specialist in Proteomics

Drexel University: Electronic Instrumentation Specialist

FDA: Staff Fellow Scientist: Chemist

Shimadzu: Field Technical Support Specialist – Chemist

Georgetown University: Postdoctoral Position in computational cancer metabolomics

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University of Maryland: Assistant Research Scientist

Posted: May 11, 2019
Location: College Park, Maryland

The Department of Cell Biology and Molecular Genetics at the University of Maryland, College Park is seeking an individual with exceptional promise or an excellent record of research for an Assistant Research Scientist to maintain and operate the Proteomics Core Facility of the University.
This individual will maintain and operate Proteomic facility equipment, including an Orbitrap Fusion Lumos Mass Spectrometer and a Dionex U3000 2D nano HPLC. The Assistant Research Scientist will conduct sample analysis and project management, sample processing, instrumental analysis, data processing, and reporting results to users. Specific responsibilities will include coordination of day-to-day management of the Core Facility, including training users, creating/maintaining fee structure and billing users, purchasing supplies and reagents, managing outside users, and reporting to an advisory committee. This individual will collaborate with researchers and assist with the writing of relevant sections in grant proposals and manuscripts. The individual will be responsible for also identifying funding opportunity announcements to maintain and improve the Proteomics Core Facility. The Assistant Research Scientist will participate in local and national mass spectrometry and proteomics events, manage the Genomics Core of the University, prepare grant applications for instrument upgrades, and deliver presentations at professional conferences.
Candidates are expected to have a PhD degree and demonstrated ability to conduct independent research.

To Apply: Please complete and on-line application at https://ejobs.umd.edu/postings/68693. Attach a Curriculum Vitae, three letters of reference and a research prospectus.

Salary will be competitive and commensurate with training and experience. The University of Maryland is an equal opportunity/affirmative action employer and encourages women and minorities to apply. For best consideration please apply before April 26, 2019.
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MedImmune: Research Bioinformatics Scientist

Posted: March 11, 2019
Location: Gaithersburg, Maryland

The Bioinformatics Scientist, located in Gaithersburg, MD, is primarily responsible for advancing scientific knowledge through the use and development of Bioinformatics tools and approaches and applying that knowledge to drug development programs and innovative research. This scientifically-passionate individual will apply their experience in the analysis, collection, mining and integration of multiple-omics data sets including proteomics, metabolomics, genomics, transcriptomics using bioinformatics and system biology approaches to advance our understanding of biological pathways and networks. The candidate will have a strong background in analyzing quantitative MS-based proteomics or metabolomics data. Direct experience developing analytical techniques and data integration methodologies in support of biomedical research is required. The successful candidate will work closely with the expanding proteomics, metabolomics and protein biochemistry group using state-of-the-art Omics technology to investigate a number of biological questions. This is a key bioinformatic position that requires comprehensive expertise and hands-on experience in this area to support drug development projects.

This role will have the opportunity work in the areas of target identification and validation, integrative informatics, big data, -omics technologies, predictive science, precision healthcare. The successful candidate, working with members of the bioinformatics team, will be responsible the delivery of data processes, tools, and methods to manage drug project information and knowledge. This role resides within R&D and will work collaboratively within Bioinformatics and across therapeutic areas and functions to design, develop, and implement tools, systems, and methods to facilitate the mining of large complex multi-platform datasets and advance our understanding of disease.

Major Duties and Responsibilities
Perform expert informatics research, including establishment of scientific hypotheses that can be approached using computational methods and tools, execution of bioinformatics projects and analyses to support biopharmaceutical projects both as directed and as opportunities present themselves
Conduct the analysis of proteomics and metabolomics data from projects at different stages of drug discovery and development. The analysis may include data ingestion, QC, pipelining, integration, functional interpretation and visualization
Support the multiomics data discovery activities through the design and delivery of novel algorithms, tools and techniques including feature detection, machine learning and intelligence
Apply the system biology approaches to elicit the biological interpretation of the multiomics datasets to provide insights into different therapeutic areas, and to enable applications such as target discovery and patient stratification
Provide technical support on the design and implementation of data management, curation and integration solutions for proteomics, metabolomics, genomics and other datasets in conjunction with R&D and external partners
Provide training and advice to project scientists on optimal use of key data, analysis
Build and manage effective relationships to ensure utilization of information resources and services. Assist with the evaluation and implementation of new and existing data and analytical systems
Provide subject matter expertise and share knowledge on computational biology tools, experimental design, data analysis methodologies, data interpretation, and novel approaches to support target discovery and validation
Develop the data infrastructure such as data pipelines and management solutions to expedite the generation and analysis of wide variety of proteomics and metabolomics studies, in conjunction with the scientists and data engineers
Promote a culture of knowledge sharing across domains to proactively support sharing of best practices among informatics and science teams
Actively identify and progress opportunities to collaborate externally in support of departmental scientific and technical goals

Education:
Advanced degree (Ph.D. or equivalent experience) in Bioinformatics, Computational Biology, Systems Biology or related field.

Essential Skills & Experience:
1-3 years of postdoctoral experience within a pharmaceutical/biotech company, academic or other relevant biomedical research environment required
Proficiency in common programming/scripting languages (e.g. R, Python, SQL, JAVA, C++, .NET) and their application in biomedical research
Demonstrated understanding in the methods of protein or metabolite identification and quantitation by mass spectrometry, and proficiency in MS bioinformatics software and analysis tools
First-hand experience in integrated analysis of large, complex proteomics and/or metabolomics datasets for biological insights, mechanisms of action, employing pathway analysis, modeling, machine learning and other approaches
Solid knowledge of informatics tools, statistical models and visualization/data mining packages (e.g. R/Shiny, genome visualization packages/browsers) and aptitude for adapting to complex new analysis packages and using them to their full potential
Familiar with machine learning, NoSQL, knowledge capture and other innovations in predictive analytics and data-driven discovery
Experiences in automated workflows in Nextflow, Galaxy or other workflow environment in HPC or cloud computing environment
Demonstrated successful experience working on multiple projects to deliver complex interpretations to cross-functional teams
Proven capacity to communicate effectively with technical and scientific colleagues alike, in formal presentations and small group meetings
Excellent written and oral communication skills
You have to demonstrate a proven record of being a fast learner, excellent communicator and thoughtful team member
You should be highly motivated, innovative, detail-oriented, creative, well organized and able to work independently when designing and executing analyses and will be expected to manage and prioritize several different projects and tasks in line with the objectives of the group

Desirable Skills & Experience:
Demonstrated knowledge and understanding of the Life Sciences Healthcare industry and how it operates is desirable
Working knowledge with software tools such as MaxQuant, ProteomeDiscoverer and others for peptide/protein identification and quantitation, XC-MS for metabolite identification and quantitation
Experience with pathway and functional analysis tools such IPA, Pathway Studio, Cytoscape, GSEA, TMHMM and SignalP
Proven track record of publishing relevant bioinformatics or systems biology results in peer-reviewed journals
Direct experience in the development and implementation of large-scale biological databases and related activities; along with experience developing rich visualizations from complex scientific data sets
Demonstrated contributions in target discovery is desirable
Demonstrated scientific knowledge of cell biology, molecular biology, or immunology, especially as it relates to biomedical research and development
Direct laboratory experience and working with biologists to design and analyze experiments is advantageous

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.
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MedImmune: Postdoctoral Fellow – Proteomics/Metabolomics

Posted: March 11, 2019
Location: Gaithersburg, Maryland

Main Duties and Responsibilities

We are seeking a skilled and innovative Postdoctoral Fellow with extensive mass spectrometry (MS) experience. In this predominantly lab-based role, the successful candidate will be involved in the establishment of novel MS-based methods at the beginning of the drug development process. The candidate will explore both proteomics and metabolomics and contribute to ongoing efforts in the lab to expand omics capabilities. The position requires the ability to embrace new technologies and methods quickly as well as perform in a fast-paced, highly collaborative work environment. The candidate will have general knowledge of the fields of chemistry, biology, mass spectrometry, proteomics, and metabolomics. The analytical instruments in the lab include: Agilent 6560 IM-QTOF, Sciex QTRAP 6500, Thermo Orbitrap Fusion, Thermo Orbitrap ID-X, Thermo Q Exactive HF-X coupled to micro- and nano-ESI along with an EVOSEP One platform and 908 Devices ZipChip platform.

Education
PhD (in Chemistry, Analytical Chemistry, Biochemistry, or related discipline)

Essential Requirements
Significant hands-on experience with mass spectrometry instrumentation.
Hands-on experience in at least ONE area of MS-based omics such as proteomics, peptidomics, metabolomics, or lipidomics.
Familiar with separation techniques such as liquid chromatography (LC) and/or capillary electrophoresis (CE).
Experience in preparation and analysis of biological matrices.
Ability to work outside established field of expertise.
Proven ability to work well collaboratively in a team environment; report results internally to fellow researchers through weekly meetings and externally through conference presentations and peer-reviewed publications.

Desirable Requirements
Experience with any of the mass spectrometers listed above.
General familiarity with MS data analysis software and bioinformatics tools for metabolomics and/or proteomics studies.
Experience with protein/peptide/metabolite quantitation methods.
Experience with automation/liquid handler platforms.
Demonstrate strong written, verbal, and interpersonal communication skills.
Willingness and flexibility to operate in a fast-paced environment and adapt to changing deadlines/priorities.

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.
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MedImmune: Postdoctoral Fellow – Proteomics

Posted: March 11, 2019
Location: Gaithersburg, Maryland

This post-doctoral fellowship in Proteomics provides a unique opportunity to work with a team of experienced mass spectrometrists engaged in proteomics, mAb characterization and metabolomics. The goal is to conduct cutting-edge research to unravel key targets in drug discovery, understanding the targets in complex disease conditions using state-of-the-art tandem mass spectrometry approach to facilitate R&D scientists from ADPE, therapeutic areas from Oncology, Cardiovascular Renal Metabolism and Respiratory Diseases. In-depth knowledge of proteomics technology, data analysis skills and biological interpretation of data is necessary to successfully carry out the functions of this position.

Essential requirements:
A Ph.D. in biochemistry, chemistry, analytical chemistry or any related life science field with a focus on mass spectrometry.
Hands-on experience in carrying out protein digestion, peptide purification and mass spectrometry data analysis.
Current knowledge of proteomics technology including nanoflow LC-MS analysis, proteomics data analysis software, protein and peptide quantitation.
Knowledge of ideal mass spectrometry sample preparation from complex samples derived from various biological sources including cells, tissues, and body fluids.
Experience in operating and troubleshooting mass spectrometry instruments.
Excellent scientific writing, presentation and communication skills.

Desirable Requirements
Experience in analysis of a wide variety of post-translational modifications.
Ability to independently carry out validation experiments in cell culture models.
Understanding of statistical tools and basic knowledge of bioinformatics analysis of the data using pathway analysis tools such as GO, IPA, KEGG and Cytoscape.
Motivation to develop new tools for MS analysis and MS data analysis and constantly update with the current knowledge in the Omics field.
Publications in high impact journals and scientific talks in conferences.

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.
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MedImmune: Scientist I – Metabolomics

Posted: March 11, 2019
Location: Gaithersburg, Maryland

Main Duties and Responsibilities
You will work in the laboratory as member of the expanding proteomics, metabolomics and protein biochemistry group using state-of-the-art metabolomics technology to investigate a number of biological questions. This is a key metabolomics application position that requires comprehensive expertise and hands-on experience in this area. You must be passionate about life science and lab bench work. You must also have a thorough understanding of modern mass spectrometry and chromatography. You will support the operation and maintenance of advanced state-of-the-art nanoflow liquid chromatography and mass spectrometry (LC-MS) instrumentation (Q-Exactive HF-X, Orbitrap ID-X, Agilent IMS-QTOF) that enable cutting-edge metabolomic profiling and translational research across our therapeutic areas.

You have demonstrated a proven record of being a fast learner, excellent communicator and thoughtful team member.

You should be highly motivated, innovative, detail-oriented, creative, well organized and able to work independently when designing and executing experiments and will be expected to manage and prioritize several different projects and tasks in line with the objectives of the group. Your projects may include development of novel metabolomic technologies or application of already existing ones to address current challenges in biology, and may entail mass spectrometric analysis of cancer cell lines, tissue samples from animal models and patient material.
Essential Requirements

Ph.D. in Metabolomics Mass Spectrometry, Analytical Chemistry or related field.
2-5 years of post-doctoral experience in a relevant research area.

The position is a hands-on, laboratory-based position.
Prior experience in quantitative metabolomics technology development and/or nano-liquid chromatography and mass spectrometry (LC-MS; ideally on Q-Exactive HF-X, Orbitrap ID-X, and/or Agilent IMS-QTOF).
The candidate should be familiar with the entire metabolomics pipeline (including sample preparation, LC and MS operation, data analysis) and must be able to conduct independent and creative research.
Ability to demonstrate scientific productivity.
Possess excellent oral and written communication skills.
An analytical aptitude for devising innovative scientific or technical solutions is highly desired.
Demonstrate enthusiasm, motivation, attention to detail and willingness to learn new technologies, flexibility and confidence.
Proven ability to publish in peer-reviewed journals, generate technical report summaries and protocols.

Desirable Requirements
Experience in working in a matrix environment.
Ability to collaborate across multiple disciplines to investigate drug candidates and disease properties.
Experience with Compound Discoverer and XC-MS is a plus.
Experience with writing bioinformatics scripts is a plus.

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.
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MedImmune: Senior Scientist – Proteomics/Metabolomics

Posted: March 11, 2019
Location: Gaithersburg, Maryland

Main Duties and Responsibilities
You will be an important contributor of the expanding proteomics, metabolomics and protein biochemistry center of excellence using state-of-the-art proteomics technology to investigate a number of biological questions. This is a key proteomics application position that requires comprehensive expertise and hands-on experience in this area. You must be passionate about life science and lab bench work. You must also have a thorough understanding of modern mass spectrometry and chromatography and will lead a small team from the bench. You will support the operation and maintenance of advanced state-of-the-art nanoflow liquid chromatography and mass spectrometry (LC-MS) instrumentation (Orbitrap Fusion, Q-Exactive HF-X, Orbitrap ID-X, Agilent IMS-QTOF, QTRAP6500) that enable cutting-edge proteomic profiling and translational research across our therapeutic areas.

You have to demonstrate a proven record of being a fast learner, excellent communicator and thoughtful team member.

You should be highly motivated, innovative, detail-oriented, creative, well organized and able to work independently when designing and executing experiments and will be expected to manage and prioritize several different projects and tasks in line with the objectives of the group. Your projects may include development of novel proteomic or metabolomic technologies or application of already existing ones to address current challenges in biology and may entail mass spectrometric analysis of cancer cell lines, tissue samples from animal models and patient material.

Essential Requirements
Ph.D. in Proteomics, Metabolomics, Mass Spectrometry, Analytical Chemistry or related field.
7-10 years of post-doctoral experience in a relevant research area.
The candidate should act as a leader from the bench, driving research programs, strategies, and ideas to completion.
Possess prior experience in quantitative metabolomics and/or proteomics technology development and/or nano-liquid chromatography and mass spectrometry (LC-MS; ideally on Orbitrap Fusion, Q-Exactive HF-X, Orbitrap ID-X, Agilent IMS-QTOF, and/or QTRAP6500).
The candidate should be familiar with the entire metabolomics and/or proteomics pipeline (including sample preparation, LC and MS operation, data analysis) and must be able to conduct independent and creative research.
An analytical aptitude for devising innovative scientific or technical solutions is highly desired.
Manage multiple collaborative projects between multiple laboratories.
Demonstrate scientific productivity and have excellent oral and written communication skills.
Drive collaborative efforts cross-functionally and with external stakeholders.
Lead a small team of scientists.
Demonstrate enthusiasm, motivation, attention to detail and ability to learn new technologies, flexibility and confidence.

Desirable Requirements
Ability to collaborate across multiple disciplines to investigate drug candidates and disease properties.
Experience with working in a matrix organization.Experience with molecular biology, including cell culture and immunochemistry is highly desired.
Experience with writing bioninformatic scripts.
Experience with robotic automation.
Experience with MaxQuant, Skyline and XC-MS is a plus.

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.
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Waters: Mass Spectrometry Sales Specialist

Posted: March 8, 2019
Location: Virginia, Maryland and Washington DC

Waters is seeking a dynamic individual to fill the role of a Mass Spectrometry Specialist. Responsibilities include driving sales of our Mass Spectrometer product line including tandem quadrupole and time of flight instruments – as well as promote solutions across all product lines including LC, Software, Consumables and Services, for the region. The desired candidate should be a self starter in developing and implementing a Territory Business Plan working in unison with their assigned account managers, specialists and marketing colleagues in delivering an aggressive call cycle and business development activities. The foundation of the Mass Spectrometry Specialist role is to develop a keen understanding of the customers’ needs and challenges, designing solutions with lasting and meaningful business impact to our customers.

This territory will cover Virginia, Maryland and Washington DC.

Responsibilities:
Meet or exceed annual sales targets
Maintain customer satisfaction among our user base
Aggressively develop new prospects and penetrate competitive accounts
Visit customers on a daily basis to highlight Waters solutions and help customers with their challenges
Build technical competency on Waters solutions and to be perceived by customers as a credible resource
Keep current on vertical markets dynamics, application trends, and competitive information
Provide information to marketing team to create business development programs
Fully utilize our Sales contact management tools and applications
Submit accurate and timely monthly reports and sales forecasts
Develop business through monthly plans of action

Qualifications:
Degree BS/Master/PHD in scientific areas such as chemistry, biology, biochemistry or related field of science
At least 3 years Mass Spec experience, UPLC, HPLC, field sales and/or marketing is a plus
Action orientation and self-driven for results
Good communication and presentation skills
Good organization / planning / time management skills
Strong interpersonal skills and a good listener
Mature disposition, positive attitude and strong sense of commitment
Adaptive to dynamic and changing environment
Strong technical background in analytical technologies

Company Description
For over 50 years, Waters Corporation has developed innovative analytical science solutions to support customer discoveries, operations, performance, and regulatory compliance. Specifically, the company designs, manufactures, sells, and services high performance liquid chromatography, ultra performance liquid chromatography, and mass spectrometry technology systems and support products primarily in the United States, Europe, Japan, and Asia. Our innovations enable significant advancements within the pharmaceutical, life science, biochemical, industrial, food safety, environmental, academic and government industries. Waters is a publicly traded corporation (NYSE:WAT) with more than 6,000 employees and is represented in over 100 countries around the world.

Apply online: https://uscareers-waters.icims.com/jobs/9366/2018-9366/job
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MilliporeSigma: Scientist, Product Characterization

Posted: February 22, 2019
Location: Rockville, MD

Your Role:
Perform analysis of testing performed within the Product Characterization Laboratory. May act as subject matter expert in Analytical Chemistry for studies performed in the Product Characterization laboratory. Will develop/validate and perform GMP methods.

PURPOSE OF THE POSITION
The Scientist will oversee a wide variety of safety testing required to manufacture clinical and commercial products. The Scientist will be the primary scientific resource for a given study with the Product Characterization lab within the overall Biologics department. The Scientist is responsible for making observations and ensuring all documentation is in compliance with procedures and regulations.

ESSENTIAL JOB FUNCTIONS
Provides day to day technical support to the laboratory.
Performs analysis and interpretation of data.
Prepares/ reviews protocols and final reports.
May serve as study director and ensures timely initiation and completion of all studies.
Ensures testing is performed in accordance with SOPs and regulations (cGMP and GLP) for custom/non routine and new services.
Participate and/or drive assay development/ assay transfer and/or assay validation activities.
Justify business needs and drive implementation of new services.
Operates and maintains lab equipment as required by SOPs and testing procedures.
Responsible for resolving deviations/ completing event records.
Liaise with Quality Assurance and appropriate cross-functional departmental areas to close the events and corrective actions identified during GxP laboratory testing.
Maintains high level knowledge of lab procedures and assays.
Responsible for creating revising SOPs, laboratory records and other related documentation.
Coaches/ trains others on developing and enhancing day to day laboratory techniques.
Contributes ideas and suggestions to improve standard laboratory techniques, protocols, processes and equipment.
Regarded as a subject matter expert (SME)
Provide technical advice and support for internal and external interactions such as client and regulatory audits/inspections, meetings, teleconferences.
Promote a culture of continuous improvement within Biologics; act as champion on initiatives and/or projects to drive improvement in quality and / or client service.
Contributes/ authors scientific publications and presents at conferences/ seminars.
Leads projects that cross multiple disciplines.
Complies with company health and safety regulations and procedures.
Performs other duties as assigned

Education:
Ph.D. in scientific discipline with 2 or more years of relevant experience
MA/MS in scientific discipline with 4 or more years relevant experience
BA/BS in scientific discipline with 6 or more years relevant experience

Experience:
Relevant working knowledge and experience in Analytical Chemistry executing and overseeing technical projects and/or related studies
Experience leading and/or supervising staff in a laboratory setting
Experience with some or all of the following technical disciplines;
Liquid Chromatography
Mass Spectrophotmetetry – performing the following tests;
Molecular weight
Peptide mapping
Glycan Profiling
N-Terminal Sequencing
UHPLC methods
Capillary Electrophoresis Methods (CE, cIEF)

Job Requisition ID: 186053
Location: Rockville
Career Level: C – Professional (1-3 years)
Working time model: full-time

Apply Online
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USDA: Postdoctoral Associate

Posted: February 14, 2019
Location: Beltsville, MD

The USDA Agricultural Research Service Food Composition and Method Development Laboratory in Beltsville, Maryland is seeking a post-doc associate in Analytical Chemistry or a closely related field. HPLC and MS experience are required. The position is primarily responsible for developing methods using LC/MS, LC/MS/MS, and/or UV/Vis for fingerprinting, identification, and/or quantification of key bioactive compounds in herbs, dietary supplements, and foods.

Interested parties should send applications to pei.chen@ars.usda.gov.
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FDA CBER: Postdoctoral Fellow

Posted: February 12, 2019
Location: Bethesda, MD

The Food and Drug Administration Center for Biologics Evaluation and Research is seeking a motivated post-doctoral individual to join The Division of Bacterial, Parasitic & Allergenic Products Laboratory of Bacterial Polysaccharides Vaccine Structure Group. The successful candidate will work with an experienced research team to investigate the structural aspects of glycoconjugate based vaccines.

The position will focus on mass spectrometry based approaches for analysis of glycoproteins and other glycoconjugates particularly in the area of vaccine antigens. Glycan array technologies will also be implemented to study viral pathogen interactions with host glycoconjugate receptors. These studies will facilitate a better understanding of how glycosylation can impact on vaccine performance and how glycosylation impacts the host-pathogen interface. This position requires a Ph.D. in chemistry, biochemistry, structural biology or a related science. New graduates are welcome to apply. A background in mass spectrometry is required. Experience in carbohydrate, proteomics mass spectrometry and/or glycan array is a plus. The laboratory’s research crosses the boundaries between analytical chemistry, structural biology, biochemistry and microbiology. The laboratory develops state of the art mass spectrometric and glycan array platforms for use in FDA mission critical projects centered in issues surrounding glycosylation of key vaccine antigens. Excellent communication skills (oral and written) and the ability to work in a team environment are required.

Salary will be commensurate with qualifications and experience. To be considered for this position, please write or email your Curriculum vitae to:

John F. Cipollo, Ph.D.
Principal Investigator
Center for Biologics Evaluation and Research
Division of Bacterial, Parasitic and Allergenic Products
Food and Drug Administration
10903 New Hampshire Avenue
Building # 52/72 and Room # G310
Silver Spring, MD 20993-0002
Office 240-402-9445
John.cipollo@fda.hhs.gov
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Georgetown University Medical Center: Analytical Scientist

Posted: February 7, 2019
Location: Washington, DC

The Goldman lab in the Department of Oncology and the Clinical and Translational Glycoscience Research Center (CTGRC) at Georgetown University Medical Center, Washington, DC invite applications for a position of Analytical Scientist with experience in mass spectrometry of (glyco)proteins. This person will join an experienced interactive team of mass spectrometrist, informaticians, and glycobiologists to optimize glycoproteomic workflows for a project funded by the Common Fund Glycoscience program (commonfund.nih.gov/Glycoscience/fundedresearch) and to apply them to translational research including personalized medicine and cancer immunology. Experience in chromatographic separations and mass spectrometry of proteins is required; the applicant will operate an Orbitrap Fusion Lumos w ETD/UVPD (Thermo) and TripleToF 6600 and QTRAP 6500 (Sciex). Experience in glycobiology and glycoproteomics is recommended. Minimum requirements include a PhD degree and a productive publication record. Candidates must have strong written and oral communication skills, be able to work independently, and work efficiently in a collaborative research environment. The selected applicants will be considered for a postdoctoral fellowship or a research track faculty position in line with their experience and accomplishments. To apply, send your CV, statement of research interests with highlighted relevant experience, and names and contact of three references to Dr. Radoslav Goldman at rg26@georgetown.edu.
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Georgetown University: Postdoctoral Fellow/Research Associate/Specialist in Proteomics

Posted: December 21, 2018
Location: Washington, DC

Georgetown University School of Medicine is seeking a Post-Doc Fellow or PhD level Research Associate/Specialist to perform proteomics services and apply cutting-edge proteomic techniques for basic and translational biomedical research. The candidate will work in a proteomics core lab and the newly established Thermo-Georgetown Precision Immuno-Oncology Center. The candidate is expected to help maintain the state-of-the-art mass spectrometry instruments and play a key role in strengthening the method development for protein/peptide analysis, especially on PTM-omics (mainly phosphorylation and glycosylation) in diseases. The candidate will have plenty of opportunities to collaborate with scientists of very diverse background (including physicians) on campus, neighbor institutions (including NIH/FDA) and pharmaceutical companies in the Washington DC metropolitan area.

Key Responsibilities included:
1. Operate, maintain, and troubleshoot advanced LC-MS/MS systems
2. Develop analytical methods for the identification and quantification of proteomes/peptidomes in diseases (especially cancer)

Requirements:
1. Strong hands-on skills handling high resolution mass spectrometers from Thermo (e.g., Orbitrap series) and Sciex (e.g., TripleTOF 5600/6600, Q-TRAP 6500)
2. Extensive hands-on experience in proteomic workflows (including sample prep., data acquisition, and data analysis), especially for phosphoproteomics and glycoproteomics
3. Enriched experience with isotopic labeling and label-free proteomic quantification methods
4. Familiar with software and bioinformatic tools for proteomic data analysis
5. Good communication and English-writing skills
6. Highly motivated and self-driven with the flexibility to quickly adapt to different projects
7. Willing to supervise and train students and fellows

Please contact Dr. Junfeng Ma (jm3004@georgetown.edu) should you have any questions about this position. To those who are interested, you can also send a cover letter and your CV with contact information of 3 references to Dr. Junfeng Ma (jm3004@georgetown.edu). In the cover letter, please briefly describe your research experience, career plan, earliest starting date, etc. The position is open immediately and we anticipate filling the position as soon as possible. Very competitive salary and benefits can be provided to the candidate depending on experience level.
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Drexel University: Electronic Instrumentation Specialist

Posted: December 14, 2018
Location: Philadelphia, PA

Maintain departmental mass spectrometers, perform high resolution mass spectral analyses, and participate in the repair and maintenance of departmental instruments. Demonstrated proficiency is required in modern MS (including experience with both GC and HPLC/UPLC as performed on hyphenated instruments) with a willingness to serve as an analytical instrument resource on methods and applicability for research projects as needed. Responsibility for daily running of samples on several departmental mass spectrometers to support research and teaching needs of the Chemistry Department. (Current high resolution sample load is 100+/month). Most samples are verification of synthesis to within 5 ppm molecular composition certainty, but exploratory investigations are also common. Maintenance includes weekly cryogen filling and mass calibration, source cleaning, pump maintenance and episodic minor and major repairs. Also maintain the daily capability for walk-up operation of the department’s Veeco/Bruker Multimode AFM. Must become familiar with the computer software associated with each instrument. Duties will include minor repair of smaller instruments around department and rebuilding of hardware components of instruments as required. Effective interpersonal skills are expected for communication with a diverse group of faculty, students, and postdoctoral scholars. Expected to train selected students on operation of instruments.

Major duties will include maintenance and operation of departmental mass spectrometers. Other duties include participation in the repair and maintenance of departmental instruments. Other duties as assigned.

The applicant should have an M.S. degree in chemistry with extensive experience or a Ph.D. degree in chemistry.

www.drexeljobs.com/applicants/Central?quickFind=84072

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FDA: Staff Fellow Scientist: Chemist

Posted: November 22, 2018
Location: College Park, MD

The Office of Regulatory Science (ORS) of the U.S. Food and Drug Administration’s Center for Food Safety and Applied Nutrition is seeking an outstanding analytical or bioanalytical chemist with mass spectrometry expertise to participate in our food safety/food defense research program. An opening for a Staff Fellow Chemist is available in the Bioanalytical Methods Branch. The position will involve the development and validation of methods for the quantification of unapproved compounds, plant toxins, and botanical constituents in dietary supplements using mass spectrometry (MS)-based techniques (i.e. LC-MS and/or GC-MS). A Ph.D. degree in Analytical Chemistry, Bioanalytical Chemistry or related fields, with a strong background and interest in MS instrumental analysis, is required. Candidates should be experienced with the latest liquid chromatographic and mass spectrometric techniques and application of those techniques to trace quantitative analysis. Training or experience in analytical method development for complex matrices such as food, cosmetics, or environmental analysis is also highly desirable. U.S. Citizenship or Permanent Resident status is required.

Interested candidates should submit a curriculum vitae, a list of references and a cover letter that includes a short statement of experience and research interests via email to: Christine Parker, Chief, Bioanalytical Methods Branch (Christine.Parker@fda.hhs.gov). Please use “Staff Fellow 2018” in the subject line.
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Shimadzu: Field Technical Support Specialist – Chemist

Posted: November 14, 2018
Location: Columbia, MD

Shimadzu Scientific Instruments is one of the largest suppliers of analytical instrumentation, physical testing, and environmental monitoring systems in the world. Our products include Gas Chromatographs, Liquid Chromatographs, Mass Spectrometers, Total Organic Carbon Analyzers, UV-Vis Spectrometers, Fluorescence, Atomic Absorption, IR, X-Ray, and Universal Testing Machines. In 1975, SSI Corporate Headquarters was established in Columbia, Maryland and we currently have nine regional offices coast to coast.

Shimadzu Scientific Instruments is hiring a Field Technical Support Specialist to provide pre-sales / post-sales support in the following product areas: HPLC, GC, UV-Vis, GCMS, LCMS, FTIR, TOC, AA, ICP, ICP-MS. This is a great opportunity for someone with hands-on experience with these instruments to work in a customer facing setting who would like to advance their career! The employee will be primarily supporting the Mid-Atlantic Sales Region. Details are below:

Position Summary:
The individual in this position is responsible for providing technical support primarily for the sales territory and secondarily for the region. He or she assists on demonstrations and sales calls, does installations, trains customers and regional personnel as well as help customers adapt methodology for our instruments.
This position is required to assist the sales efforts by installing instruments and training customers in their uses at customer sites. The incumbent must have problem solving skills, which are required to solve customer and regional problems. This position’s primary focus is to provide technical expertise for the selling effort of the region.

Job Function(s):
1. Assist with Demonstrations and sales calls.
2. Perform Installations.
3. Help customers adapt methodology for our instrumentation.
4. Assist the Product Managers in achieving customer satisfaction.
5. Manage and maintain the regional demonstration inventory.
6. Assist and consult on regional and customer training.
7. Assist the Regional Manager as necessary.
8. Must travel overnight, as the position requires.
9. Must travel by air and drive as required.

Knowledge Requirements:
CASUAL WORKING THOROUGH
Training Methods
Report Preparation
Organizational Skills
Service Repair Skills
Laboratory Equipment Analytical Instrumentation
Chemistry
Customer Relations Skills
Computer Literacy
Communication Skills

Education and/or Experience:
Experience with HPLC is preferred, although experience will be considered in one or all of the following products: LC, LCMS, GC, GCMS.
A minimum of a Bachelor’s degree in Chemistry, or a closely related field and at least two (2) years of laboratory experience with analytical instrumentation is required.

Shimadzu Scientific Instruments is an Equal Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected Veteran status.

Link for application: https://rew12.ultipro.com/SHI1000/JobBoard/JobDetails.aspx?__ID=*D57280D3600445D8
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Georgetown University: Postdoctoral Position in computational cancer metabolomics

Posted: November 7, 2018
Location: Washington, DC

Georgetown University Medical Center has made a major commitment to metabolomics as a critical component to our cancer biology and systems medicine initiatives. A funded position is now available through the NCI T32 Interdisciplinary Program in Tumor Biology at the Lombardi Comprehensive Cancer Center for a computational metabolomics postdoctoral fellow. There are several areas of potential focus including: 1) statistical workflows for genomic/metabolomic cancer data integration; 2) developing informatics pipelines for high-throughput untargeted LC-MS metabolomics; 3) novel computational methods for elucidating stress signal transduction and events at the metabolic level, with particular emphasis on exposure to ionizing radiation and biomarker identification in biofluids and tissues, with extension to microbiome involvement.

Our mass spectrometry facility has assembled state-of-art instrumentation for metabolomics and is a Waters Center of Innovation, with development of untargeted and targeted approaches on LC-MS and LC-TOFMS. GC-MS, NMR, and Seahorse metabolic technologies complement the available platforms.

This metabolomics program is funded to carry out a variety of studies in animal models and patient samples, and the recruit will have opportunities to participate in and build on these projects. Experience in bioinformatics, statistical analysis, and computer programming (R, Python, Java) is required, and background in mass spectrometry, analytical chemistry, and biochemistry will also be taken into consideration. Individuals with excellent communication skills (written and oral), ability to work independently, multitasking and solving problems are encouraged to apply for a position in this dynamic lab. The current funded position requires U.S. citizenship (or green card). For more details see: http://fornacelab.georgetown.edu.

Applicants should send cover letter, resume, and names of references to Dr. A.J. Fornace Jr at af294@georgetown.edu, Dr. Evagelia C. Laiakis at ecl28@georgetown.edu, and/or Dr. Tytus D. Mak at tdm46@georgetown.edu.
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