Thursday, March 21st, 2019

2nd Annual North American Mass Spectrometry Summer School

February 1, 2019 by  
Filed under Meetings

https://www.ncqbcs.com/summer-school-2019/

July 21-24, 2019 Madison, WI

Please join us for our second annual North American Mass Spectrometry Summer School. We are proud to have assembled world-leading experts in mass spectrometry for this two and a half-day course. Students will experience an engaging and inspiring program covering fundamentals of mass spectrometry and its application to biological systems analysis. Tutorial lectures and hands-on workshops for scientific and professional development are planned. This workshop is made possible by generous support from the National Science Foundation (Integrated Organismal Systems, Plant Genome Research Program, Grant No. 1546742), the National Institutes of Health National Center for Quantitative Biology of Complex Systems (P41 GM108538), Thermo Fisher Scientific, and Promega. Applications for Mass Spec Summer School close on March 15, 2019 at midnight.

Expert Instructors:
Josh Coon – University of Wisconsin
Ulrike Kusebauch – Institute for Systems Biology
Jesse Meyer – University of Wisconsin
Doug Sheeley – National Institutes of Health
Evgenia Shishkova – University of Wisconsin
Beatrix Ueberheide – New York University School of Medicine
Judit Villen – University of Washington-Seattle
Mike Westphall – University of Wisconsin
Evan Williams – University of California-Berkeley

Tutorial Lecture Topics:
Data Analysis
Mass Analyzers
Ionization
Tandem MS
Chromatography
Shotgun Proteomics, Instrument Acquisition, and Setup
PTMs

Hands-on Workshops:
Data Integration
Mass Spec 101
Negotiations
Intellectual Property
Science Writing
Scientific Illustrations
Spectral Interpretation
NIH funding and grant process

Organizing Committee: Evgenia Shishkova, Laura Van Toll, and Josh Coon…

February 2019 Meeting (note location change)

January 15, 2019 by  
Filed under Meetings, WBMSDG Meetings

Speaker: W. Andy Tao, Purdue University

Topic: Analyses of Protein Phosphorylation and Their Applications in Liquid Biopsy

Date: Monday, February 11, 2019

Time: 6:15 pm Dinner, 7:15 pm Presentation

Location: University of Maryland College Park, room 1208, Biology-Psychology building, 4066 Campus Drive, College Park, MD 20742 (parking: 200 Regents Dr, College Park, MD 20742) (Directions)

Dinner: Please RSVP to Yan Wang (yanwang@umd.edu) by Friday, February 8th if you will be attending dinner.

Abstract: Protein kinases and their substrates comprise extensive signaling networks that regulate many diverse cellular functions. However, methods and techniques to systematically identify kinases directly responsible for specific phosphorylation events have remained elusive. Here we describe integrated proteomic strategies to dissect kinase networks in high throughput and demonstrate their applications in multiple systems. Our group has introduced a set of chemical tools and proteomics strategies to analyze protein phosphorylation, in particular, to identify direct kinase substrates and upstream kinases. Recently, for the first time, we identified thousands of phosphoproteins isolated from small volumes of plasma samples and quantitatively measured phosphoproteins that are significantly higher in patients diagnosed with breast cancer as compared to healthy controls. Our studies demonstrate that the development of phosphoproteins as disease biomarkers is highly feasible and may transform disease early detection and monitoring.…

CANCELLED FOR WEATHER (January 2019 Meeting)

December 19, 2018 by  
Filed under Meetings, WBMSDG Meetings

Speaker: Asher Newsome, Smithsonian Museum Conservation Institute

Topic: Ambient Sampling and Ionization for Mass Spectrometry of Museum Objects and Materials

Date: Monday, January 14, 2019

Time: 6:15 pm Dinner, 7:15 pm Presentation

Location: Shimadzu Scientific Instruments, Inc. Training Center 7100 Riverwood Drive, Columbia, MD 21046 (Directions)

Dinner: Please RSVP to Yan Wang (yanwang@umd.edu) by Friday, January 11th if you will be attending the dinner.

Abstract: Over thirty years after the creation of an atmospheric pressure ionization source for mass spectrometry, development of ambient sampling and ionization sources for use without chromatography exploded beginning in 2004. Whether a given technique moves from academia to industry or follows some other path, oftentimes a design originally intended to be a general-purpose analytical MS tool – versatile, based on fundamental principles, relatively open-source – becomes increasingly engineered toward niche applications, particularly the biomedical and defense markets. With some 150 million objects (including living specimens) in its collection that have been selected for conservation and are available for study, the interests of the Smithsonian Institution fill every niche. The versatility, modularity, and throughput of our mass spectrometry systems are of the utmost concern. A varied selection of our recent projects using ambient ionization, direct analysis in real time (DART), and solid phase microextraction (SPME) to analyze ancient, historic, and modern objects is presented, as well as some of our instrumental modifications to accommodate the particular concerns of a museum.…

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