Wednesday, August 15th, 2018

39th East Coast Ion Chemistry Conference

July 31, 2018 by  
Filed under Meetings

The 39th East Coast Ion Chemistry Conference, ECICC, will be held on Saturday, October 13 in 219 Brown Lab at the University of Delaware. You and your co-workers are invited to attend. There will be refreshments and opportunities for discussion and conversations.

Talks have been given at past meetings on instrumentation (MALDI, TOF, ICR, ESI, GC/MS, API, PIAMS), ion molecule reactions, calculations, and chemical analyses. Attendance in recent years has been 30 – 40 and the presentations have lasted from ~9 am until shortly after noon.

Please let us know if you want to give a TEN (10) minute talk on one aspect of your research – not a survey of work done in the last year. We encourage presentations by graduate and undergraduate students. There is no charge to attend the meeting or to give presentations.

We would appreciate a response by the first week in October. All we need is your name, affiliation and (if you are giving a presentation) the title of your talk. No abstract is required. Titles will be accepted through noon on Thursday, October 11. The meeting is informal, but we do need a schedule. Please respond to

A parking map for the University of Delaware is here. There is a large (pay, unfortunately) parking garage on Academy Street, near Brown Lab.

We hope that you will be able to attend and present some of your work.
Murray Johnston, Burnaby Munson, Doug Ridge…

NIH Proteomics Seminar

July 27, 2018 by  
Filed under Meetings

Special guest speaker seminar on Tuesday, 7/31/18 at NIH in Bethesda, MD: room 4-433, 2-3 pm.

Prof. Dr. Lihua Zhang
National Chromatographic R. & A. Center
Dalian Institute of Chemical Physics, Chinese Academy of Sciences

“New Methods For Proteome Analysis, From Quantitation To Interaction”

Due to the complexity of samples, with the wide dynamic range in abundance, the diverse physical chemical properties, and the changes with time and space, the development of novel methods for proteome analysis is imperative.

In our recent work, ionic liquid, 1-dodecyl-3-methylimidazolium chloride, was selected to improve the solubility of proteins, especially for hydrophobic proteins, and simultaneously ensure the compatibility with the subsequent tryptic digestion and MS detection. Furthermore, ionic liquid based filter assisted sample preparation (i-FASP) protocol was proposed, and demonstrated the superiority to the commonly used SDS or urea based FASP method, to achieve the deep coverage proteome qualitation and quantitation.

A fully automated sample treatment (FAST) device was designed, by which proteome samples, no matter for proteins extracted from cells, tissues or plasma, could be on-line denatured, alkylated and digested within 20 min. Moreover, FAST could be integrated with any commercial LC-MS/MS instrument, to achieve the automated proteome quantitation, by which the throughput, accuracy, precision and coverage was improved obviously, compared with the off-line multi-step operation, especially for label-free quantitation.

Furthermore, various novel chemical crosslinkers were designed to achieve the comprehensive study on protein-protein interaction.

All the above mentioned methods have been applied to achieve the deep coverage proteome analysis in various fields, such as life science, precision medicine and food safety.…

Waters Mass Spectrometry Users Meeting

July 9, 2018 by  
Filed under Meetings

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