Saturday, July 4th, 2015

Notices

June 8, 2015 by admin  
Filed under Meetings

1.June 15, 2015 Meeting in Columbia; Topic: Post-ASMS Poster Session and Dinner with Presentations by 2015 Travel Award Recipients

2.2015 MSDG Young Investigator Travel Awards

3.Mass Spectrometry in Biology and Medicine (MSBM) Summer School, Dubrovnik, Croatia, July 5-11, 2015

4.12th Symposium on the Practical Application of Mass Spectrometry in the Biotechnology Industry (Mass Spec 2015); Brooklyn, New York; September 22-25, 2015

June 2015 Meeting

June 8, 2015 by admin  
Filed under Meetings

Topic: Post-ASMS Poster Session and Dinner with Presentations by Travel Award Recipients

Date: Monday, June 15, 2015

Time: 6:15 pm: Dinner,Social Hour and Poster Presentations; 7:30 pm: Presentations by Travel Award Recipients

Location: Shimadzu Scientific Instrument, Inc. Training Center 7100 Riverwood Drive, Columbia, MD 21046 (Directions)

Dinner and Social Hour Please RSVP to Asher Newsome (graham.newsome.ctr@nrl.navy.mil) if you will be attending dinner.

2015 MSDG Travel Award Recipients:

Wenjing Li, University of Maryland, Baltimore (Advisor: Maureen Kane): Use of native mass spectrometry for quantification of protein complex

Rosemary Onjiko, George Washington University (Advisor: Peter Nemes): Single Cell Mass Spectrometry Reveals Cell Heterogeneity in the 16 cell Frog (Xenopus laevis) Embryo

Linwen Zhang, George Washington University (Advisor: Akos Vertes): Metabolic Analysis of Single Human Cells by Capillary Microsampling Electrospray Ionization Mass Spectrometry and Stable Isotope Labeling

May 2015 MSDG Meeting

May 3, 2015 by admin  
Filed under Meetings

Speaker: Professor Mary T. Rodgers, Department of Chemistry, Wayne State University

Topic: Structures and Glycosidic Bond Stability of DNA and RNA Nucleosides Probed by a Synergy of Theory and Tandem Mass Spectrometry Techniques

Date: Monday, May 11, 2015

Time: 6:15 pm: Dinner and Social Hour; 7:15 pm: Presentation

Location: Shimadzu Scientific Instrument, Inc. Training Center 7100 Riverwood Drive, Columbia, MD 21046 (Directions)

Dinner and Social Hour Please RSVP to Asher Newsome (graham.newsome.ctr@nrl.navy.mil) if you will be attending dinner.

Abstract: Nucleosides are N-glycosides of ribose and 2′-deoxyribose, the basic building blocks of nucleic acids: ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). Reactions leading to glycosidic bond cleavage are of great interest for a variety of reasons; in particular, they are amongst the most common reactions involved in DNA repair and nucleobase salvage. Protonation or noncovalent interactions with metal cations facilitate cleavage of the glycosidic bond and are therefore generally involved in the enzymatic processes that lead to glycosidic bond cleavage in biological systems. In this presentation, I will discuss the use of a variety of tandem mass spectrometers (guided ion beam tandem, quadrupole ion trap, and Fourier transform ion cyclotron resonance) and mass spectrometry techniques (energy-resolved collision induced dissociation (ER-CID) under single and multiple collision conditions as well as wavelength resolved infrared multiple photon dissociation (IRMPD) action spectroscopy) and synergistic electronic structure calculations to elucidate the structures and glycosidic bond stability of a variety of DNA and RNA nucleosides. Trends as a function of nucleobase identity, the presence or absence of the 2′-hydroxyl substituent, and modifications will be examined.

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