2009 Young Investigator Travel Award Recipients

The Washington-Baltimore MSDG is pleased to announce the recipients of this year’s Young Investigator Travel Awards.  4 recipients were judged to be deserving of an award.

Joshua Wilhide, University of Maryland- Baltimore County (Advisor:  Prof. Dan Fabris):  Investigating higher-order structure of nucleic acids by IRMPD in FTICR mass spectrometry.  Award: $600

Omoruyi Osula, Johns Hopkins University (Advisor:  Prof. Bob Cotter):  Analytical Methods for Improving Identification of SUMO-Modified Peptides.  Award: $300

Katherine Stamper, Johns Hopkins University (Advisor:  Prof. Bob Cotter):  Combining ChIP Antibodies and Mass Spectrometry to  Study Post-Translational Modifications on Histones.  Award: $200.

Colin Wynne, University of Maryland (Advisor: Catherine Fenselau):  High confidence identification of bioagent biomarkers using top-down analyses on an Orbitrap.  Award: $100.

May 18, 2009 WBMSDG Meeting

Differential phosphorylation and accumulation of nuclear proteins associated with defense responses in plants

Speaker: Dr. Bret Cooper, Soybean Genomics and Improvement Laboratory
USDA-ARS, Beltsville, MD  20705

Date: Monday, May 18, 2009

Time: 7:30 pm

Location: Shimadzu Scientific Instrument, Inc. Training Center, 7100 Riverwood Drive, Columbia, MD 21046

Please join Miquel Antoine and the speaker for dinner at the Ram’s Head Tavern at Savage Mill, 8600 Foundry Street, Savage, MD 20763 at 5:30 pm.  Contact Miquel at Miquel.Antoine@jhuapl.edu and let her know you will be there.

Abstract: Approximately 5,000 proteins from soybean nuclei were detected using a high-throughput liquid chromatography triple-mass spectrometry method.  Statistics of summed spectral counts revealed sets of proteins with differential accumulation changes between soybeans susceptible and resistant to the soybean rust fungus.  These protein accumulation changes were compared to gene expression changes and very little overlap was found.  Differential phosphorylation state changes were also observed.  Many of the differential accumulation or modified proteins have predicted nuclear localization signals and have homology to transcription factors and other nuclear regulatory proteins. These results suggest that numerous plant defense responses are post-translationally regulated in the nucleus.  It is possible that these proteomic changes influence several down-stream defense responses that ultimately confer immunity.

Washington-Baltimore MSDG Travel Award Announcement

The Washington-Baltimore Mass Spectrometry Discussion Group will be awarding one or more grants to outstanding young investigators to support travel to the 2009 ASMS meeting in Philadelphia, PA. It is expected that one or more awards worth $500 will be made. The award is open to undergraduate and graduate students at all levels in laboratories and institutions traditionally associated with the Washington-Baltimore MSDG (approximate boundaries: Richmond and Charlottesville on the south and Newark, Delaware on the north). Applicants should submit an electronic copy (PDF or Word format preferred) of their ASMS abstract, an additional two page summary of their research project (figures can be included), a CV or resume, and a letter of recommendation from their advisor, to:

Dr. Miquel Antoine
Johns Hopkins Applied Physics Laboratory
11100 Johns Hopkins Rd., MS 2-217
Laurel, MD, 20723
(443)778-6904
FAX:(240)228-6904
e-mail: Miquel.Antoine@jhuapl.edu

Applications should be submitted no later than May 8, 2009. A panel of senior MSDG members will act as reviewers and the awards will be announced in the third week of May, 2008. Successful applicants will be expected to present a 15-20 minute presentation at the post-ASMS poster session on June 15, 2009. Please pass this announcement along to anyone that you think would be interested.

February 23, 2009 WBMSDG Meeting

Speaker: Dr. Stephen Stein
National Institute of Standards and Technology
Gaithersburg, MD

Topic: Tandem Mass Spectral Libraries

Location: Shimadzu Scientific Instrument, Inc. Training Center
7100 Riverwood Drive, Columbia, MD 21046
Go here for more detailed directions to this location: Shimadzu directions

Please join Miquel Antoine and the speaker for dinner at the Ram’s Head Tavern at Savage Mill, 8600 Foundry Street, Savage, MD 20763 at 5:30 pm.  Contact Miquel at Miquel.Antoine@jhuapl.edu and let her know you will be there.

Time: 7:30 pm

Abstract: Reference mass spectra are widely used for compound identification by GC/MS, though rarely used for ‘small molecule’ LC-MS/MS and almost never used in proteomics. An overview of our work on MS/MS library construction and use over the past few years will be presented, including libraries for proteomics, reference materials, recurrent spectra and proteomics, and their use in a QA/QC pipeline.