Available Positions

Metropolitan Museum of Art: Research Associate

Metropolitan Museum of Art: Senior Research Assistant

University of Illinois at Chicago: Assistant Director of Research of Mass Spectrometry Core

Drexel University: Chemistry Department Instrument Specialist

NIST and NC State: Postdoctoral Scientist

mProbe: Scientist

Shimadzu: Product Specialist – GCMS

Shimadzu: Mass Spectrometry (MS) Service Specialist

Shimadzu: LCMS Sales Specialist

AstraZeneca: Scientist I

AstraZeneca: Bioinformatics Scientist I

AstraZeneca: Senior Bioinformatics Scientist

Georgetown University: Postdoctoral Fellow

FDA White Oak: Postdoctoral Fellow

Johns Hopkins University: AIMS Core Laboratory Technologist

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Metropolitan Museum of Art: Research Associate

Posted: December 28, 2019
Location: New York, NY

This role entails scientific analytical development and optimization tailored to the interrogation of complex cultural heritage materials under the supervision of a Research Scientist. Duties will include developing, implementing, and evaluating novel mass spectrometric (MS) approaches for the study of composite samples from artworks. This is a one-year full time position funded by the Richard Lounsbery Foundation.

PRIMARY RESPONSIBILITIES & DUTIES:
• Assists in the development, implementation and evaluation of novel MS approaches for analysis of cultural heritage materials including but not limited to proteins, polysaccharides and lipids in collaboration with The University of Bordeaux, France.
• Researches, plans, conducts, and documents, protocol development in collaboration with The University of Bordeaux.
• Establishes and implements MS analysis protocols at the museum.
• Develops and utilizes databases and applications to streamline the documentation and dissemination of results.
• Fosters relationships with art conservators, historians and archaeologists from partner museums within an interdisciplinary research environment.
• Performs literature reviews of scientific and conservation publications, proposing improvements to existing protocols and procedures.
• Writes progress and summary reports, standard operating procedures (SOPs), and annotated bibliographies on related topics and activities.
• Develops platforms and activities for public engagement, as well as writes scientific articles, papers, reports or books, as appropriate.
• Other duties as assigned

REQUIREMENTS & QUALIFICATIONS:
Experience and Skills:
• Demonstrated expertise in mass spectrometry and advanced liquid chromatographic analytical techniques (LCMS, MALDI-MS) (required).
• Development and implementation of sample preparation, analysis methods and protocols for MS analysis of proteins, polysaccharides or lipids (omics methods) (required).
• Development and implementation of sensitive methods and protocols for the evaluation of degraded or modified proteins, polysaccharides or lipids (preferred).
• Experience in chemical interactions and/or crosslinking (preferred).
• Implementing advanced statistical analysis methods on scientific data (preferred).
• Development of process automation using modern database software and web-enabled
tools (preferred).
Knowledge and Education:
• Ph.D. in chemistry, biochemistry, engineering, materials science, related disciplines or equivalent experience (required).
• Experience working in museum environments, specifically, either with or in proximity of art objects (preferred).
• Strong command of both written and spoken English (required).
• Ability to work in partnership on location at the University of Bordeaux in Bordeaux, France for up to one month. (required).

Effective Date: March 2020
End Date: 1 year from date of hire

Inquire with Julie Arslanoglu at Julie.Arslanoglu@metmuseum.org
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Metropolitan Museum of Art: Senior Research Assistant

Posted: December 28, 2019
Location: New York, NY

This role provides scientific instrument and methodology support under the supervision of a Research Scientist. Duties will include testing, implementing, and evaluating new sample preparation methodologies and mass spectrometric (MS) analysis for the evaluation of protein-containing art related materials. Duties also include the preparation and artificial ageing of replica samples; coordination of sample collection, distribution, and analytical results from three institutions; perform and evaluate sample preparation methodologies by MS. This 9-month full time position is funded by the Richard Lounsbery Foundation.

PRIMARY RESPONSIBILITIES & DUTIES:
• Assists in the evaluation of novel and established sample preparation methodologies for analysis of cultural heritage using established advanced MS analytical techniques and protocols including but not limited to proteins.
• Prepare samples according to established and/or new protocols for proteomics and other omics analyses.
• Accompany samples and either perform MS analysis or alternatively work with collaborators to perform MS analysis.
• Researchers, plans, conducts, and documents, the creation of replica exemplar materials as well as artificial ageing protocols, followed by characterization of the artificially aged material.
• Plans, conducts, and documents the collection and dissemination of replica and authentic samples to collaborating institutions.
• Manages and collects data from collaborating institutions.
• Performs literature reviews of scientific and conservation publications, proposing improvements to existing protocols and procedures.
• Writes progress and summary reports, standard operating procedures, and annotated bibliographies on related topics and activities.
• Develops platforms and activities for public engagement, as well as writes scientific articles, papers, reports or books, as appropriate.
• Other duties as assigned

REQUIREMENTS & QUALIFICATIONS:
Experience and Skills:
• Strong laboratory experience in organic, biological, or biochemical chemistry (preferred).
• Experience preparing protein or other materials for analysis by ELISA, LC/MS or MALDI (preferred).
• Experience operating and analyzing data from at least two analytical tools. Examples
include but are not limited to optical spectroscopy, Raman or IR spectroscopy, liquid or gas chromatography, mass spectrometry, ELISA or MALDI (required).
• Familiar with statistical analysis of data (preferred).
• Previous museum experience (preferred).
• Proficient in Microsoft Word processing, Excel spreadsheet manipulation, and use of
PowerPoint for documenting, processing, and presenting information (required).
• Strong organizational skills (required).
• Strong command of both written and spoken English (required).
Knowledge and Education:
M.S. in chemistry, biochemistry, materials science, or biology, or BS with equivalent training and experience. (required)
Strong general chemistry and organic chemistry lab experience. (required)
Strong command of both written and spoken English. (required)

Effective Date: January 2020
End Date: 9 months from date of hire

Inquire with Julie Arslanoglu at Julie.Arslanoglu@metmuseum.org
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University of Illinois at Chicago: Assistant Director of Research of Mass Spectrometry Core

Posted: December 18, 2019
Location: Chicago, IL

Description:
This position assists the Director of MSC in overseeing the operations of an analytical Mass Spectrometry research facility. Defines research projects, carries out own research projects, and trains other lab personnel in various techniques and research equipment. Custom designs and performs Mass Spectrometry associated research projects according to customer needs. Carries out complex laboratory protocols and data analysis. Assists in preparation and submission of shared instrument and other grant applications.

Duties:
Consult with prospective users (faculty, clinicians, fellows and graduate students) on appropriate methodologies to accomplish their research goals.
Train Research Specialists and Senior Research Specialists in new protocols and supervise their routine performance.
Design and test custom research protocols as needed. Modify existing protocols as appropriate.
Test, customize and implement new techniques and write comprehensive protocols.
Prepare substantial portions of grant applications as requested. Serve as a co-investigator on funded grants.
Assist the Director in preparation and submission of shared instrument grants.
Oversee the operation and maintenance of highly-specialized instrumentation. Supervise the backup and storage of research data acquired at the facility.
Analyze and document results for publication and reports. Assist in manuscript preparation and review as requested. Develop presentations based on research findings/results.
Assist Director with the facility’s financial management, such as lab budgeting using accounting practices, interact with finance directors and IT to deliver invoices in a timely fashion.
Perform other related duties and participate in special projects as assigned.

Qualifications:
Minimum of a Master’s Degree in Science or related field with 5 years of experience in Analytical Sciences using Mass Spectrometry or a PhD’s Degree in Science with 3 years of experience.
A minimum of 1 year of laboratory research experience in LC/MS and targeted assay by SRM/MRM.
A minimum of 1 year of lab management experience required.
A minimum of 1 year purchasing for laboratory, inventory maintenance, communication with vendors and contracting required.
A minimum of 1 year laboratory maintenance, including equipment maintenance and installation required. Preferred lab experience with the following technologies:
Protein/peptide/small molecule sample preparation
Global quantitative proteomics, targeted/untargeted metabolomics
Bioinformatics analysis

Preferred experience with lab budgeting, including accounting practices and billing for services rendered.

Apply at https://jobs.uic.edu/job-board/job-details?jobID=125160&job=assistant-director-of-research-of-mass-spectrometry-core-msc
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Drexel University: Chemistry Department Instrument Specialist

Posted: December 9, 2019
Location: Philadelphia, PA

Responsibilities of the position include the oversight of departmental chemical analysis and mass spectrometry instrumentation, which includes troubleshooting and minor repair, routine
maintenance, calibration, and the training of users. The ideal candidate would likely not be an expert at the operation of all of the instruments listed below already, but has a curiosity and a willingness to learn those instruments or techniques that they don’t already know.

Time breakdown
Instrument repair and calibration: 45%
Instrumentation related training or meetings: 30%
Instrument computer support: 15%
Administrative tasks (email and searching for specialized parts/ordering): 10%

Departmental Instrumentation
Perform routine maintenance and periodic calibration
Troubleshoot and perform minor repairs in collaboration with manufacturer or third-party service
personnel
Arrange for instrument service when required
Train users (undergraduate, graduate, post-doctoral associates, visiting researchers, faculty, etc.) in the
proper use of the instruments
Serve as analytical instrument resource for research project needs
Maintain information about instrumentation on the department’s website
Maintain hardware and software upgrades for instrumentation.
Maintain a supply of consumables, supplies, and gases for instruments
Maintain computers interfaced with the department instrumentation
Maintain a clean & safe working environment in the various instrument facilities
Assist other department Electronics Instrument Specialists in the MS or NMR facility when required
Run high-resolution MS samples for faculty and/or their students

The position requires excellent communication skills, the ability to work independently, and the ability to work productively with individuals of varying backgrounds and levels of expertise.

Current Instrumentation: flame atomic absorption spectrometer w/graphite furnace accessory, fluorescence spectrometer, capillary column gas chromatograph, capillary column gas chromatograph/mass spectrometer system, quaternary gradient ultra-high performance liquid chromatograph, quaternary gradient high performance liquid chromatograph, binary gradient high performance liquid chromatograph triple-quadrupole mass spectrometer system, Fourier-transform infrared absorption spectrometer w/attenuated total reflectance sampling accessory, Fourier transform infrared microscope, thermogravimetric analyzer, (3) UV/visible absorption spectrometers (one including a solid state diffuse reflectance accessory), laser diffraction particle size analyzer, circular dichroism spectrometer, capillary electrophoresis system, computer interfaced electronics workstation, including multiple NI ELVIS II/III systems and Quanser Analog Electronics Lab Suite (Analytical Instrumentation Lab, Disque 407); (6) Ocean Optics USB spectrometers, BAS electrochemical system, Fourier-transform infrared absorption spectrometer, UV/visible absorption spectrometer (Disque 409); (2) Fourier- transform infrared absorption spectrometers, 2 capillary column gas chromatographs, high performance liquid chromatograph, microwave synthesizer, 90MHz Fourier-Transform Nuclear Magnetic Resonance Spectrometer (PISB 502); (2) optical microscopes, Nanodrop UV/visible absorption spectrometer, capillary electrophoresis system, gel imaging system, ISS fluorescence polarization spectrometer, ISS fluorescence lifetime spectrometer (Department Microscopy Facility, Stratton 416); Fourier-transform infrared absorption spectrometer, (2) Renishaw UV/visible Raman microscope/spectrometer systems, dynamic light scattering spectrometer (Vibrational Spectroscopy Lab, Disque 113); Thermo-Finnigan LTQ-FT FT-ICR Mass Spectrometer w/Thermo Surveyor HPLC, Bruker Autoflex III MALDI TOFMS, Applied Biosystems 4800 Proteomics Analyzer, Micromass ZQ single quadrupole mass spectrometer w/Waters Alliance 2695 HPLC system and Waters model 2998 DAD, Micromass Quatro Micro triple-quadrupole mass spectrometer w/Agilent 1100 HPLC system, Micromass Q-TOF Premier w/Waters Alliance 2695 HPLC system and Waters model 2998 DAD, (Chemistry Department MS Facility, Stratton 406).

If interested, please apply directly to Drexel Careers using at: https://careers.drexel.edu/en-us/job/494161/instrumentation-specialist
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NIST and NC State: Postdoctoral Scientist

Posted: November 22, 2019
Location: Rockville, MD

A postdoctoral scientist position is available for a collaborative research project between the Biomanufacturing Training and Education Center at NC State and the National Institute of Standards and Technology in Rockville, MD. The candidate will be embedded at the National Institute of Standards and Technology in Rockville, MD. The research teams focus on basic and applied sciences in the field of biotechnology that provides solutions to major scientific problems important to society.

The candidate will develop innovative approaches toward characterization of next generation biotherapeutics (e.g. gene therapy viral vectors) using mass spectrometry. The successful candidate will join a group of well-established experimentalists focused on biopharmaceutical protein characterization; providing the candidate an extensive and diverse collaborative environment.

The successful candidate should have or be nearing completion of a PhD in Analytical Chemistry, Biochemistry, or related field and an excellent publication history. Experience in mass spectrometry is a requirement, with an emphasis on proteomics and/or protein characterization preferred. He/she will be expected to work within a network of internal and external collaborators, engage stakeholders and display the potential to become a recognized leader in the field.

Apply at https://jobs.ncsu.edu/postings/125790
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mProbe: Scientist

Posted: November 22, 2019
Location: Rockville, MD

Department: Discovery Proteomics, R&D

Purpose
We are seeking a Mass Spectrometry Scientist to join the Discovery Proteomics Group in mProbe (Rockville, MD). The incumbent will be an integral part of the Company’s expansion to discovery efforts focusing on innovative clinical assays for precision medicine in cancer. Major duties include but are not limited to establishing robust workflow of LC-MS-based proteomics for discovery pipeline, increasing company’s analytical capacity on global proteomics, maintenance of LC-MS platforms to the highest quality, and large-scale data analysis using PRM/SRM and DIA/DDA approaches. The successful candidate will be highly motivated to work within a science focused, collaborative and multidisciplinary team environment to achieve the company’s goal of providing solutions for precision medicine.

Essential Functions
• Develop and implement LC-MS workflows for discovery proteomics and define analytical strategies for large-scale data analysis. Perform characterization of clinical samples (tissue and serum/plasma) by molecular profiling and provide quantitative data. Responsible for hands-on instrumentation including Quadrupole-Orbitrap, Triple-Quadrupole, and nano-LC in GLP/CLIA settings.
• Optimize the analytical performance (sensitivity and selectivity) of LC-MS-based clinical assays by scientific and technological improvement. Evaluate new technologies and integrate them into the discovery pipeline to increase productivity and robustness.
• Support Project Teams to assist Pharma and Clinical Research Projects by conducting MS experiments, and by contributing to generation of study plan and study reports.
• Develop and maintain standard operating procedures (GLP, CLIA) by authoring SOPs and implementing the current SOP for maintenance of GLP and CLIA facility. Contribute to manuscript submission and to patent application.

Qualification and Knowledge/Skills Required
• Ph.D. in analytical chemistry, biochemistry or related field with 0-5 years post-doctoral experience.
• Strong fundamental knowledge of protein chemistry and understanding of biology of genomic alternations with proteomic phenotype.
• Solid LC-MS background and expertise in proteomics methodologies. Hands-on experience with Quadrupole-Orbitrap mass spectrometry, nano-LC fluidics, and data processing with various software.

Experience with PRM/SRM and DDA/DIA.
• Experience with large-scale data analysis and bioinformatics. Problem solving skills based on understanding of raw data.
• Excellent oral and written communication skills. Passion for science and innovation.
• Strong and collaborative work ethic. Self-starter – individual needs to be persistent in achieving mProbe’s scientific and business objectives.

Other comments or specific duties:
This position requires the employee to work in a laboratory environment, which can create the potential for occupational exposure to biological or chemical hazards.

Please submit your CV to Sheeno Thyparambil, PhD (sheeno@mprobe.com) to apply for the position.
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Shimadzu: Product Specialist – GCMS

Posted: November 20, 2019
Location: Columbia, MD

Position Summary:
The individual in this position is responsible for a wide variety of GCMS support related functions including, but not limited to, development of technical documents related to marketing, sales, application use, training, repair, maintenance, installation, and phone support of Shimadzu GCMS product line. Travel and customer contact to support assigned product may be required. Additional responsibilities include training customers and SSI staff, as well as, other related duties that may be assigned from time to time.

Additional Function(s):
Providing support to sales staff for GCMS products from a marketing perspective.
Develop demonstration strategies and presentation of GCMS products to potential and current customers to support the sales effort.
Obtain and maintain competitive information for GCMS products and analyze for report to sales.
Assist in the creation of documentation for sales support materials including feature/benefit analysis and positioning strategies for GCMS products.
Evaluate and recommend market needs and then propose to develop and implement hardware and software resolutions to meet these needs.
Support qualification tests for large corporate customers and round robin tests with ASTM and other official organizations.
Support instrument quality procedures in house and in the field.
Perform applications work as required effectively positioning the GCMS products, and analyzing customer samples. Perform methodology adaptation work for customers as needed.
To produce customer support materials to further sales for the GCMS product line (such as brochures, technical notes, application notes flyers, etc…)
Operate as the company’s authority on the GCMS products, market position, and competitive strategy under the area of responsibility.
The application, operational and maintenance support of those products sold by SSI or its representatives.
Develop and provide technical training courses and materials for customers and SSI employees.
Develop a knowledge base through the accurate documentation and reporting of product failures and repairs.
Provide product design change and improvement recommendations.
Assist in the development of installation and maintenance procedures for products as required.
Maintain the current IQ/OQ/PT protocols and develops protocols for new products.
Maintain assigned instruments in application laboratories.
Travel as required, in order to effectively provide technical support of the GCMS product line.

Scope:
This position’s primary focus is to provide technical marketing materials and education to efficiently support product positioning of the GCMS products, as well as, provide timely and efficient support, of high quality, to our customers. This will include the full scope from product design to customer satisfaction, coordinating efforts with the Marketing team, Sales, Service, and the Regional staff.

Knowledge Requirements / Education / Experience:
The incumbent must be proficient at effectively troubleshooting operational, application and other GCMS instrument problems in a methodical efficient manner. Additionally, the incumbent must be able to act independently in matters not governed by policy to ensure customer satisfaction.

Education and/or Experience:
The incumbent is required to have at least a Bachelor’s degree in the physical or natural sciences, with a higher level degree highly preferred. At least two years of technical applications/method development experience directly related to the GCMS product line is required. Experience in maintenance and/or repair of analytical instrumentation, marketing background and any sales experience is highly desirable. Attention to detail and strong customer service skills are required along with a dependable work ethic.

Apply: https://recruiting.ultipro.com/SHI1000/JobBoard/2bc2a753-1232-400c-84cf-ef90d5762b76/OpportunityDetail?opportunityId=8a3c1346-33eb-4aaa-8320-bba642264da9
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Shimadzu: Mass Spectrometry (MS) Service Specialist

Posted: November 20, 2019
Location: Miami, FL

SSI is currently hiring a Mass Spectrometry (MS) Service Specialist to cover the Southern Florida Service Region. Strong attention paid to experience with LCMS products. This position will be based in the Miami / Ft. Lauderdale, FL area. A position description is as follows:

Position Summary:
The individual in this position is responsible for a wide variety of service related support functions including, but not limited to, the repair, maintenance, after hours phone support and installation of Shimadzu products. Additionally, responsibilities include the training and support of regional staff and less experienced personnel. As well, other related duties may be assigned from time to time.

This position is responsible for the repair, maintenance, and installation of those products sold by Shimadzu Scientific Instruments anywhere within the company’s market area. Direct area of support is the regional territory for Mass Spec and related products.

ADDITIONAL FUNCTIONS INCLUDE, BUT ARE NOT LIMITED TO:
The repair, maintenance, and installation of those products sold by Shimadzu Scientific Instruments or its representatives.
Providing technical service training to customers, service and technical support personnel.
Accurate documentation and reporting of all repairs and product failures; and when applicable, providing design change and improvement recommendations.
Assist in the development of preventative maintenance procedures for Shimadzu products as required.
The maintenance and control of repair parts inventories within the position’s assigned region in accordance with the administrative policies as defined by the Service Center in Columbia, Md.
Providing customers and other personnel with the necessary technical support (phone, FAX, E-Mail etc.) and documentation required to effect instrument repairs, maintenance, and installations.
Phone Support to include after hours (night and weekend) technical assistance to customers anywhere within the SSI market area.
Repairing instruments returned to the Regional Service Center in a timely manner.
Travel to provide service support to customers and other SSI personnel.
Timely submission of all required paperwork and reports.

SCOPE:
This position’s primary focus is to provide quality, efficient service to our customers and to support the other Service, Technical Support, and Sales & Marketing staff in the performance of the same. Will report directly to the Regional Service Manager and will work in conjunction with Corporate Service management as needed.

KNOWLEDGE REQUIREMENTS:
CASUAL
Leadership Skills
WORKING
Organizational Skills
Report Preparation
Lab Procedures
Japanese Culture
Training Methods
THROUGH
Chemistry
Computers & Software
Use of Electronic Test Equipment
Mechanical Knowledge
Product Knowledge – Mass Spec
Customer Service Skills
Instrument Repair & Maintenance

PROBLEM SOLVING REQUIREMENTS:
Incumbent must be proficient at effectively troubleshooting and resolving instrument problems, performing installations, and providing, when necessary, customer and staff training. Incumbent must also be capable of successfully running standard samples and reading/interpreting the chromatography to determine if the instrument is functioning properly. Must be able to resolve basic and complex applications related customer problems, through exercising independent discretion and judgment based learned industry specific knowledge and company policies/protocol.

EDUCATION AND/OR EXPERIENCE REQUIREMENTS:
A bachelor’s degree in Chemistry or a closely related field is required, while an advanced degree is preferred. Incumbent should have at least one (1) year (while two or more is highly preferred) of field exposure supporting mass spec instrumentation, or the equivalent experience. Must be proficient in LCMS instrumentation.

Apply: https://recruiting.ultipro.com/SHI1000/JobBoard/2bc2a753-1232-400c-84cf-ef90d5762b76/OpportunityDetail?opportunityId=e37742ef-8057-44c5-8717-13b86fb8d0df
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Shimadzu: LCMS Sales Specialist

Posted: November 20, 2019
Location: Marlborough, MA

Shimadzu Scientific Instruments is hiring a Sales Specialist – LCMS for our North Atlantic Sales territory, based in Marlborough, MA. This person will be responsible for selling our high end LCMS instrumentation (Triple Quad) as well as other Life Science / Biotech products. This position affords the ability to have an excellent base salary, uncapped commissions, and a company vehicle! Details are below:

Position Summary:
The sales specialist in this position is responsible for a wide variety of sales related functions including sales of all assigned product lines to include demonstrations, installs, training and reporting. This position has a goal to meet or exceed the Regional Life Science and LCMS forecasted goal. Sales specialist shall close and support these opportunities/sales by utilizing their abilities as well as, other related duties that may be assigned from time to time.

This position will be required to reach or exceed assigned sales goals within an assigned geographic territory. Will be utilized as a product expert and assist other regional personnel on the sales closure of all Life Science opportunities. Sales specialist will also facilitate post sales technical support for the assigned products.

Additional Functions:
To become proficient in all Life Science products; by maintaining a high level of technical skills in all areas related to the assigned products.
To assist regional efforts in making sales calls, maintaining good customer relationships, demonstrations, installations, training and providing technical support.
To assist the regional personnel in identifying and closing Life Science sales opportunities.
To develop demonstrations strategies and presentations of products to potential and current customers to support the sales efforts.
To obtain competitive information for assigned products and analyze – report finding to Managers and Marketing.
To evaluate, recommend and forecast market needs and then propose to develop and implement hardware and software resolutions to meet these needs to Life Science Marketing Manager.
To provide input in the creation of documentation for sales support materials including feature/benefit analysis and positioning strategies for each product assigned to marketing.
To assist with applications work as required effectively positioning the product and analyzing customer samples.
To develop a knowledge base through the accurate documentation and reporting of product failures and repairs.
To help develop and provide technical training and materials for customers and SSI employees.
To provide product design change and improvement recommendations.
To maintain assigned instruments in application labs.
Significant travel in the United States, in order to support, the assigned product line is required. This travel may be by air or by car.
Maintenance and safekeeping of all assigned company property.

Scope:
This position’s primary focus is to achieve sales goals while maintaining excellent customer relations and reporting back to the Regional and Home Offices those factors, both good and bad, that affect the assigned territory.

Knowledge Requirements:
CASUAL
Japanese Culture
SSI Sales Organization
Competitive Knowledge
WORKING
Training Skills
Report Preparation
Organizational Skills
Laboratory Equipment
Competitive Knowledge
Systems Troubleshooting Ability
THOROUGH
LCMS Applications
Systems Troubleshooting Ability
Chemistry Knowledge
Communication Skills
Application Skills
Analytical Techniques
Competitive Knowledge
Computers
Biotech Products

Education and/or Experience:
The sales specialist must have excellent problem solving, technical, application and operational skills related to Chemistry and Mass Spectrometers; in order to find customer solutions and meet regional sales goals while ensuring customer satisfaction. Incumbent must have at least one product proficiency badge, from company internal developmental program.

A minimum of a BS Degree in Chemistry or Biochemistry, with a Ph.D. being highly preferred. At least one year of laboratory experience with LCMS and one year of sales experience.

Education
Bachelors or better in Chemistry or related field.
Preferred
Masters or better in Chemistry or related field.

Apply: https://recruiting.ultipro.com/SHI1000/JobBoard/2bc2a753-1232-400c-84cf-ef90d5762b76/OpportunityDetail?opportunityId=4cd81562-1540-4d2a-af4e-4c679fdd6e0f
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AstraZeneca: Scientist I

Posted: October 29, 2019
Location: Gaithersburg, MD

About the role
You will work in the laboratory as member of the expanding Dynamic Omics group and be actively involved in developing and implementing pipelines for metabolomics and proteomics applications to support the analysis of clinical samples. This position will be primarily focused on utilizing state-of-the-art proteomics and metabolomics technologies to investigate a number of biological questions in support of our clinical research and requires comprehensive expertise and hands-on experience in these areas. You must be passionate and enthusiastic about clinical and translational research and poses an in-depth understanding and hands-on experience with modern mass spectrometry and chromatography techniques. You will be responsible for establishing standardized methods and procedures for sample handling, processing and analysis as well as troubleshooting mass spectrometry instrumentation and automated platforms. A primary responsibility will be the operation of advanced nanoflow liquid chromatography and mass spectrometry (LC-MS) instrumentation (Fusion, Q-Exactive HF-X, Orbitrap ID-X, Agilent IMS-QTOF, TIMS-TOF, QTRAP) to support innovative proteomics and metabolomics profiling and translational research across our therapeutic areas, which include cardiovascular, renal, metabolic and respiratory diseases.

In addition to developing and maintaining technological capabilities, this role will involve planning and conducting laboratory experiments and interpreting complex proteomic and metabolomic data. Additionally, this position will closely collaborate with scientists in the Proteomics and Metabolomics, Flow Cytometry and Imaging groups and support Translational Scientists to set and implement biomarker strategies. Give the scope of this dynamic role and the need to multitask, it is essential to be a fast learner, excellent communicator, well organized, innovative and able to work independently when designing and executing experiments as well as to manage and prioritize tasks. Furthermore, you should demonstrate enthusiasm, motivation, attention to detail and willingness to learn new technologies, flexibility and confidence.

Essential Requirements
Ph.D. in Proteomics, Mass Spectrometry, Analytical Chemistry, Biochemistry or related field.
Sci I: 3-6 years of post-doctoral experience in a relevant research area; without prior supervisory responsibility.
The position is a hands-on, laboratory-based position.
Experience with processing and analysis of biological matrices (urine, serum, plasma, fluids, tissue)
The candidate should be familiar with the entire proteomics pipeline (including sample preparation, LC and MS operation, data analysis) and able to conduct independent and innovative research.
Extensive experience with method validation, QC selection and implementation, standardization for proteomics and metabolomics workflow and pipeline development.
Experience with specific instruments (Fusion, Q-Exactive HF-X, Orbitrap ID-X, Agilent IMS-QTOF, TIMS-TOF, QTRAP) preferred.
Exceptional proficiency with MS data analysis software (MaxQuant etc.), bioinformatics and statistics tools
Strong written and oral communication skills
Proven ability to publish in peer-reviewed journals, generate technical report summaries and SOPs.
Able tp work well collaboratively in a team environment.

Desirable Requirements
Experience developing and optimizing automation/liquid handler platforms.
Knowledge and working experience with CLSI guidelines, familiarity with CLIA regulations
Experience with high-throughput analysis of diverse clinical specimens
Ability to collaborate across multiple disciplines

View and apply
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AstraZeneca: Bioinformatics Scientist I

Posted: October 14, 2019
Location: Gaithersburg, MD

About the role
You will work as member of the expanding Dynamic Omics group and be actively involved in developing and implementing pipelines for metabolomics and proteomics applications to support the analysis of preclinical and clinical samples. This position, sitting in Gaithersburg, MD, will be primarily focused on getting insight from large-scale omics data investigating a number of biological questions in support of our preclinical and clinical research and requires comprehensive expertise in omics data interpretation. You must be passionate and enthusiastic about omics data and possess fundamental understanding of mass spectrometry-based omics data. You will be responsible for writing scripts and develop tools to analyze, integrate and visualize complex data sets. You will analyze quantitative mass spectrometry proteomics and metabolomics data for untargeted and targeted omics experiments. You will understand quantitative proteomics and metabolomics workflows and data structure to efficiently integrate and/or develop automated data acquisition, processing, analysis and visualization protocols, with appropriate infrastructure and pipeline management tools. You will develop appropriate QC tools to monitor and improve data acquisition. You will be responsible for maintaining and developing our applications for omics insight. You will contribute to local and global data management processes and solutions for capturing and exploiting omics and other high-dimensional data types such as transcriptomics and genomics. You will effectively collaborate with biologists, bioinformaticians, statisticians and other data scientists to design and deliver robust and impactful multiomics studies, via data processing, analysis and interpretation. This includes design of experiments, analysis of omics data in conjunction with other data types via statistical, multivariate and machine learning approaches. You will combine open-source and/or commercially available software platforms for enabling protein and metabolite identification & annotation across multiple biosamples (cell lines, body fluids, tissues). In addition, this role will work closely together with other bioinformaticians and data scientists primarily focused on developing the infrastructure for automated data processing.

Finally, this position will closely collaborate with scientists in the Proteomics and Metabolomics, Transcriptomics, Flow Cytometry and Imaging groups and support Translational Scientists. Give the scope of this dynamic role and the need to multitask, it is essential to be a fast learner, excellent communicator, well organized, innovative and able to work independently when designing and executing experiments as well as to manage and prioritize tasks. Furthermore, you should demonstrate enthusiasm, motivation, attention to detail and willingness to learn new technologies, flexibility and confidence.

Essential Requirements
As a Bioinformatician Sci1 your skills and qualifications will include:
PhD in bioinformatics, mathematics, computer science, statistics, engineering or the life sciences with 1-3 years of experience in mass spectrometry-based omics data analysis
Demonstrable experience in some of the following core competency areas: Mass-spectrometry based omics, multivariate and/or high dimensional data analysis (-omics), data management and visualization
Experience with some relevant software tools such as Python, R, Perl, Shiny, Javascript, C/C++, SQL/NoSQL databasing, networked and cloud-based systems, software versioning tools (e.g. Git/Github)
Familiarity with issues related to normalization, imputation and analysis of LC-MS omics data
Ability to successfully contribute innovative and novel scientific analyses across line platform projects
Possess a basic understanding of molecular biology, cell biology, and human physiology
Ability to communicate and collaborate effectively with scientists across a broad range of disciplines

Desirable Requirements
Experience in multi-omics integration would be advantageous

View and apply
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AstraZeneca: Senior Bioinformatics Scientist

Posted: October 14, 2019
Location: Gaithersburg, MD

About the role
You will work as member of the expanding Dynamic Omics group and be actively involved in developing and implementing pipelines for metabolomics and proteomics applications to support the analysis of preclinical and clinical samples. This position, sitting in Gaithersburg, MD, will be primarily focused on getting insight from large-scale omics data investigating a number of biological questions in support of our preclinical and clinical research and requires comprehensive expertise in omics data interpretation. You must be passionate and enthusiastic about omics data and possess fundamental understanding of mass spectrometry-based omics data. You will be responsible for writing scripts and develop tools to analyze, integrate and visualize complex data sets. You will analyze quantitative mass spectrometry proteomics and metabolomics data for untargeted and targeted omics experiments. You will understand quantitative proteomics and metabolomics workflows and data structure to efficiently integrate and/or develop automated data acquisition, processing, analysis and visualization protocols, with appropriate infrastructure and pipeline management tools. You will develop appropriate QC tools to monitor and improve data acquisition. You will be responsible for maintaining and developing our applications for omics insight. You will contribute to local and global data management processes and solutions for capturing and exploiting omics and other high-dimensional data types such as transcriptomics and genomics. You will effectively collaborate with biologists, bioinformaticians, statisticians and other data scientists to design and deliver robust and impactful multiomics studies, via data processing, analysis and interpretation. This includes design of experiments, analysis of omics data in conjunction with other data types via statistical, multivariate and machine learning approaches. You will combine open-source and/or commercially available software platforms for enabling protein and metabolite identification & annotation across multiple biosamples (cell lines, body fluids, tissues). In addition, this role will work closely together with other bioinformaticians and data scientists primarily focused on developing the infrastructure for automated data processing.

Finally, this position will closely collaborate with scientists in the Proteomics and Metabolomics, Transcriptomics, Flow Cytometry and Imaging groups and support Translational Scientists. Give the scope of this dynamic role and the need to multitask, it is essential to be a fast learner, excellent communicator, well organized, innovative and able to work independently when designing and executing experiments as well as to manage and prioritize tasks. Furthermore, you should demonstrate enthusiasm, motivation, attention to detail and willingness to learn new technologies, flexibility and confidence.

Essential Requirements
As a Senior Bioinformatician your skills and qualifications will ideally include:
PhD in bioinformatics, mathematics, computer science, statistics, engineering or the life sciences with 4 – 10 years of experience in mass spectrometry-based omics data analysis
Demonstrable experience in the core competency areas: Mass-spectrometry based omics, multivariate and/or high dimensional data analysis (-omics), data management and visualization
Experience with relevant software tools such as Python, R, Perl, Shiny, Javascript, C/C++, SQL/NoSQL databasing, networked and cloud-based systems, software versioning tools (e.g. Git/Github)
Experience with issues related to normalization, imputation and analysis of LC-MS omics data
Contribute innovative and novel scientific analyses across line platform projects
Basic understanding of molecular biology, cell biology, and human physiology
can communicate and collaborate effectively with scientists across a broad range of disciplines

Desirable Requirements
Experience in multi-omics integration would be advantageous
Prior supervisory experience of 1-2 junior bioinformaticians would be advantageous.

View and apply
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Georgetown University: Postdoctoral Fellow

Posted: September 30, 2019
Location: Washington, DC

The Georgetown Lombardi Comprehensive Cancer Center invites applications to fill an open postdoctoral position at the Ressom Lab (http://omics.georgetown.edu). We are seeking a motivated and experienced person with a Ph.D. degree in chemistry, analytical chemistry, biological sciences or related field, who exhibits a broad analytical aptitude. The candidate is expected to have experience in sample preparation for metabolomic studies as well as operation and maintenance of LC-MS/MS and GC-MS instruments. Specifically, the successful candidate will work on untargeted analysis of metabolites in human tissues and blood samples by LC-MS/MS and GC-MS. In addition, the candidate is expected to have relevant skills and experience in targeted quantitation of metabolites by parallel reaction monitoring (PRM), selected reaction monitoring (SRM), and single ion monitoring (SIM).

Please e-mail your CV and names of three references to hwr@georgetown.edu
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FDA: Postdoctoral Fellow

Posted: September 19, 2019
Location: Silver Spring, Maryland

Under the guidance of a mentor, the selected fellow will conduct research on protein pharmaceuticals using UHPLC, LC/MS and high resolution MS. This research will aim to link processing parameters to critical quality attributes of therapeutic proteins. The participant will conduct analysis and experimentation in the laboratory utilizing prescribed procedures (protocols, standard operating procedures, etc.), and will document and report data in a timely manner according to regulatory guidelines. S/he will perform much of their research on (U)HPLC, Orbitrap MS and Q-IM-TOF MS in the FDA White Oak Facility.

Candidates please email Dr. Jinhui Zhang at Jinhui.zhang@fda.hhs.gov
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AIMS Core Laboratory Technologist

Posted: September 9, 2019
Location: Baltimore, Maryland

Duties and responsibilities:
This technical position is to perform sample preparation, matrix-assisted laser desorption/ionization (MALDI) imaging, and data analysis in the new Applied Imaging Mass Spectrometry (AIMS) Core (https://johnshopkins.corefacilities.org/service_center/show_external/3815) at The Johns Hopkins Medical Institutions. The candidate will closely work with and support the users of the AIMS Core under the supervision of the AIMS Core director Dr. Kristine Glunde. He/She is expected to section frozen or formalin-fixed paraffin-embedded (FFPE) tissues obtained from users onto conductive slides, use a robotic sprayer to spray enzymes/matrix onto tissue sections, set up MALDI imaging experiments, perform histology stains, and perform imaging data analysis under guidance. The candidate is expected to be knowledgeable about MALDI imaging analysis, SCiLS lab, iLAB, MATLAB, and statistical analysis methods. The candidate is expected to prepare reports about the obtained results in powerpoint and excel to be sent to users. The candidate is expected to frequently interact with AIMS Core users, requiring good people skills. The candidate is also expected to keep the AIMS Core facility clean, monitor inventory levels, order materials and supplies as needed, and keep records of all experiments performed in accordance with established policies and procedures.

Communication:
Good people skills and good communication skills required. Exchanges information in an appropriate manner requiring good oral and written communication skills.

Education / Experience:
Required: B.Sc required. M.Sc. preferred. Preferred science courses with lab & research lab experience in chemistry and/or biochemistry. Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry or MALDI imaging experience preferred. High performance liquid chromatography (HPLC) experience preferred.

Experience:
Some related work experience preferred in a comparable lab performing MALDI mass spectrometry imaging, MALDI mass spectrometry, or other mass spectrometry imaging techniques, and/or high performance liquid chromatography (HPLC), coupled with a general knowledge of biochemistry, chemistry, biological sciences, or related field. Must be detail-oriented, keep clear experimental records, have effective organizational skills, and be able to prioritize workload appropriately. Must be able to perform multiple tasks efficiently and correctly, often operating more than one instrument at a time. Experience in laboratory procedures and good computer skills required.

Any specific physical requirements for the job: Must be able to lift 25 lbs., must be able to sit for long period of time, and must be able to climb at least 4 flights of stairs.

Supervisory responsibility (indicate the number and type of persons supervised by incumbent): 0

Budget authority (indicate dollar amount of budget managed and type/level of authority): Will work in iLAB to set up and approve billing of users. Will order supplies based on need in SAP.

Please send your application materials to Dr. Kristine Glunde at kglunde@mri.jhu.edu if you are interested in this position.
Please submit your application under the official Johns Hopkins application link as well:
https://career4.successfactors.com/sfcareer/jobreqcareer?jobId=15724
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